The Lancet Commission on TB believes that with bold leadership, smart investments based on sound science, and a shared responsibility, we will end TB within a generation.

Read the Report of the Lancet Commission on TB

The Lancet Commission set out to establish a roadmap for how high burden countries could meet the goals established by the UN High Level Meeting (UNHLM) in September 2018. The Commission's report provides a new, comprehensive analysis of how to build a TB-free world. Commissioners met regularly over a period of 18 months to try to answer the question: “How Should TB high-burden countries and their development partners target their future investments to ensure that ending TB is achieved?” The Report provides specific action items to address the barriers to building a TB-free World.

Specifically, it calls upon high-burden countries and the global community to:

Implement and Expand on Proven Strategies

  • Provide person-centered diagnosis and treatment
  • Reach all populations at high risk for TB
  • Strengthen and Deliver Prevention Strategies in tandem with active case finding interventions.
  • Prioritize private-sector engagement.
  • Provide universal access to drug susceptibility testing and ensure access to second-line DST for all persons with drug resistant TB

Investing to accelerate development of new tools

  • Invest in and accelerate the pace of TB science, innovation, and development
  • Invest in implementation, operational and programmatic research to rapidly translate research findings into TB control policies and programs to address public health needs
  • Implement and scale up the use of existing biomedical and prevention tools and strengthen the infrastructure and capacity to operationalize research findings into TB control programs
  • Deliver strong advocacy to science ministries and research-oriented pharmaceutical companies to ensure global commitment to TB R&D.

Make the case Why TB is the “Best Buy” in Global Health

  • All countries need to dedicate substantial resources to implement strategies to end TB.
  • Achieve greater domestic resource mobilization by increasing the distribution of public resources to health, pooling financing, and allocating tax revenues to health, especially in middle-income countries.
  • Increase efforts to enact new models of donor financing that focus on results, encourage innovation and strengthen government accountability

Create a New Era of Responsibility

  • Fortify the leadership and engagement of civil society in all aspects of TB programming
  • Establish a country-specific Report Card to measure progress and where more resources are needed
  • Establish a Lancet Observatory to independently evaluate progress


Overall, the Commission concludes that the prospect of a TB-free world can be achieved with the right commitment of leadership and resources. It stresses that countries must be flexible as they respond to changing demographics, patient preferences and available data.The roadmap must be focused on achieving the UNHLM goals and flexible enough to react when necessary to modify strategies.